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Chinese Journal of Injury Repair and Wound Healing(Electronic Edition) ›› 2026, Vol. 21 ›› Issue (01): 63-68. doi: 10.3877/cma.j.issn.1673-9450.2026.01.011

• Review • Previous Articles    

Research progress on the mechanism of action of probiotics in burn wound healing

Qiang Chen1, Shengjun Cao1, Quan Li1, Cuijuan Zhao2,()   

  1. 1 Department of Burn Surgery, Inner Mongolia Baogang Hospital (Third Clinical College of Inner Mongolia Medical University), Baotou 014000, China
    2 Department of Gastroenterology, Inner Mongolia Baogang Hospital (Third Clinical College of Inner Mongolia Medical University), Baotou 014000, China
  • Received:2025-11-19 Online:2026-02-01 Published:2026-01-30
  • Contact: Cuijuan Zhao

Abstract:

The healing process of burn wounds is intricate and often complicated by challenging issues such as microbial colonization and delayed healing. Thus, there is a critical need to explore novel therapeutic strategies that can accelerate wound healing and modulate the local microenvironment. As such agents, probiotics are beneficial microorganisms that exert effects including inhibiting pathogenic bacteria, promoting tissue regeneration, and modulating immune responses, thereby facilitating wound healing. Growing evidence has demonstrated that probiotic formulations hold promising potential for burn wound management. This article explores changes in burn wound microbiota composition and the role of probiotics in wound healing, by reviewing existing clinical evidence to offer insights and directions for improving outcomes and quality of life in burn patients.

Key words: Burns, Wound healing, Probiotics, Dysbiosis, Microbial regulation

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