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中华损伤与修复杂志(电子版) ›› 2026, Vol. 21 ›› Issue (05) : 389 -394. doi: 10.3877/cma.j.issn.1673-9450.2026.05.010

综述

姜黄素促进慢性难愈性创面愈合的研究进展
尹兴铠, 李正宇, 王坤, 孙树栋†()   
  1. 261000 潍坊市人民医院(山东第二医科大学第一附属医院)烧伤整形与创面修复科
  • 收稿日期:2026-03-25 出版日期:2026-10-01
  • 通信作者: 孙树栋
  • 基金资助:
    山东省中医药科技项目(M-2022055); 潍坊市卫生健康委员会中医药科研项目(WFZYY2022-03-013)

Research progress in curcumin promoting the healing of chronic refractory wounds

Xingkai Yin, Zhengyu Li, Kun Wang, Shudong Sun†()   

  1. Department of Burn and Wound Repair,Weifang People's Hospital,the First Affiliated Hospital of Shandong Second Medical University,Weifang 261000,China
  • Received:2026-03-25 Published:2026-10-01
  • Corresponding author: Shudong Sun
引用本文:

尹兴铠, 李正宇, 王坤, 孙树栋. 姜黄素促进慢性难愈性创面愈合的研究进展[J/OL]. 中华损伤与修复杂志(电子版), 2026, 21(05): 389-394.

Xingkai Yin, Zhengyu Li, Kun Wang, Shudong Sun. Research progress in curcumin promoting the healing of chronic refractory wounds[J/OL]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2026, 21(05): 389-394.

慢性难愈性创面是临床上常见的一种疾病状态,病程长且常伴疼痛,严重影响患者生活质量和心理健康。外科换药等常规治疗手段效果有限,愈合周期较长,临床治疗与康复面临较大挑战。姜黄素具有抗炎、抗氧化、促血管生成及抗菌等多重作用,逐渐成为慢性难愈性创面治疗领域的研究热点。该文对姜黄素在促进慢性难愈性创面愈合中的作用机制、临床应用现状及新型递送系统的研究进展进行综述,并探讨当前挑战与未来发展方向,旨在为姜黄素的临床应用提供参考。

Chronic refractory wounds are a common clinical condition characterized by a prolonged course and frequent pain, which severely affect patients' quality of life and mental health. Conventional treatments such as surgical dressing changes have limited efficacy and often result in extended healing times, posing considerable challenges in clinical management and rehabilitation. Curcumin, with its multiple pharmacological properties including anti-inflammatory, antioxidant, pro-angiogenic, and antibacterial effects, has increasingly become a research focus in the treatment of chronic refractory wounds. This article reviews the mechanisms by which curcumin promotes the healing of chronic refractory wounds, the current status of its clinical application, and the research progress on novel delivery systems. In addition, current challenges and future directions are discussed, aiming to provide a reference for the clinical application of curcumin.

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