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Chinese Journal of Injury Repair and Wound Healing(Electronic Edition) ›› 2021, Vol. 16 ›› Issue (05): 449-452. doi: 10.3877/cma.j.issn.1673-9450.2021.05.014

• Review • Previous Articles     Next Articles

Research progress of extracellular matrix components in promoting wound healing in biological tissue engineering

Jiahui Kou1, Mengyuan Zhang1, Baolin Zhang1,()   

  1. 1. Department of Plastic and Aesthetic Burn Surgery, First Hospital of Shanxi Medical University, Taiyuan 030001, China
  • Received:2021-07-25 Online:2021-10-01 Published:2021-11-12
  • Contact: Baolin Zhang

Abstract:

Wound healing is a complex process of regulation and control, which is related to many factors. In the application of bioengineering materials, by simulating the environment of extracellular matrix(ECM), a repair material with the best spatial structure is constructed to regulate the process of wound healing. In recent years, there are many biological tissue materials that simulate the ECM environment, and they also have a certain promoting effect on wound healing. This review will explain the mechanism of ECM regulation and promotion of wound healing, so as to provide new ideas for clinical promotion of wound healing.

Key words: Wound healing, Tissue engineering, Extracellular matrix, Hyaluronic acid, Collagen

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