New progress in preparation and clinical application of microne skin tissue

doi:10.3877/cma.j.issn.1673-9450.2021.06.013

Abstract

Abstract:

The original micro-skin grafting technology in China has been applied to repair the extremely large and deep burn wounds with severe lack of autologous skin sources and achieved remarkable results. In recent years, researchers at home and abroad have continuously improved and innovated the technology of microne skin transplantation based on the theory of microne skin transplantation, and expanded its application field. This paper mainly introduces the innovative preparation methods and equipment of microne skin tissue in recent years, and the related research progress of the innovative application of microne skin tissue in other clinical fields. With the standardization and simplification of preparation methods and processes, microne skin tissue transplantation will be applied to more and more clinical scenes, showing a good clinical effect and application prospects.

Key words: Skin transplantation, Wound healing, Cicatrix, Microne free skin graft

Haojie Gao, Shichu Xiao. New progress in preparation and clinical application of microne skin tissue[J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2021, 16(06): 528-531.

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References 26

[1]	张明良，曹大鑫，常致德，等. 微粒皮肤移植在大面积烧伤患者中的应用[J]. 中华整形烧伤外科杂志，1987, 3(1): 284.
[2]	陈旭，覃凤均，于东宁，等. 微粒皮肤移植术的历史、现状和未来[J/CD]. 中华损伤与修复杂志(电子版), 2019, 14(1): 9-12.
[3]	郑小鹏，肖仕初. 微粒皮移植现状及展望[J/CD]. 中华损伤与修复杂志(电子版), 2016, 11(6): 462-464.
[4]	Kadam D. Novel expansion techniques for skin grafts[J]. Indian J Plast Surg, 2016; 49(1): 5-15.
[5]	Tan M, Woo P. Injection laryngoplasty with micronized dermis: a 10-year experience with 381 injections in 344 patients[J]. Laryngoscope, 2010, 120(12): 2460-2466.
[6]	Trovato L, Monti M, Fante CD, et al. A New Medical Device Rigeneracons Allows to Obtain Viable Micro-Grafts From Mechanical Disaggregation of Human Tissues[J]. J Cell Physiol, 2015, 230(10): 2299-2303.
[7]	Purpura V, Bondioli E, Graziano A, et al. Tissue Characterization after a New Disaggregation Method for Skin Micro-Grafts Generation[J]. J Vis Exp, 2016(109): e53579.
[8]	Hamnerius N, Wallin E, Svensson K, et al. Fast and Standardized Skin Grafting of Leg Wounds With a New Technique: Report of 2 Cases and Review of Previous Methods[J]. Eplasty, 2016, 16: e14.
[9]	Hackl F, Bergmann J, Granter SR, et al. Epidermal regeneration by micrograft transplantation with immediate 100-fold expansion[J]. Plast Reconstr Surg, 2012, 129(3): 443e-452e.
[10]	Singh M, Nuutila K, Kruse C, et al. Pixel Grafting: An Evolution of Mincing for Transplantation of Full-Thickness Wounds[J]. Plast Reconstr Surg, 2016, 137(1): 92e-99e.
[11]	肖仕初. 皮片切割设备：中国，CN201821236341.9[P]. 2019-04-09.
[12]	Osborne SN, Schmidt MA, Harper JR. An Automated and Minimally Invasive Tool for Generating Autologous Viable Epidermal Micrografts[J]. Adv Skin Wound Care, 2016, 29(2): 57-64.
[13]	Osborne SN, Schmidt MA, Derrick K, et al. Epidermal micrografts produced via an automated and minimally invasive tool form at the dermal/epidermal junction and contain proliferative cells that secrete wound healing growth factors[J]. Adv Skin Wound Care, 2015, 28(9): 397-405.
[14]	Bassetto F, Turra G, Salmaso R, et al. Autologous injectable dermis: a clinical and histological study[J]. Plast Reconstr Surg, 2013, 131(4): 589e-596e.
[15]	Martin L, Byrnes M, Mcgarry S, et al. Social challenges of visible scarring after severe burn: A qualitative analysis[J]. Burns, 2017, 43(1): 76-83.
[16]	Kaplani K, Koutsi S, Armenis V, et al. Wound healing related agents: Ongoing research and perspectives[J]. Adv Drug Deliv Rev, 2018, 129: 242-253.
[17]	Andrews JP, Marttala J, Macarak E, et al. Keloids: The paradigm of skin fibrosis - Pathomechanisms and treatment.[J]. Matrix Biol, 2016, 51: 37-46.
[18]	Svolacchia F, De Francesco F, Trovato L, et al. An innovative regenerative treatment of scars with dermal micrografts[J]. J Cosmet Dermatol, 2016, 15(3): 245-253.
[19]	Erol OO. Facial autologous soft-tissue contouring by adjunction of tissue cocktail injection (micrograft and minigraft mixture of dermis, fascia, and fat)[J]. Plast Reconstr Surg, 2000, 106(6)：1375-1387; discussion 1388-1389.
[20]	Bocchiotti MA, Bogetti P, Parisi A, et al. Management of Fournier's gangrene non-healing wounds by autologous skin micrograft biotechnology: a new technique[J]. J Wound Care, 2017, 26(6): 314-317.
[21]	Uehara M, Shimizu F. Progress report for intractable ulcer and osteomyelitis cases using autologous micrografts[J]. SAGE Open Med Case Rep, 2019, 7: 2050313X19848301.
[22]	Armstrong DG, Orgill DP, Galiano R, et al. Complete wound closure following a single topical application of a novel autologous homologous skin construct: first evaluation in an open-label, single-arm feasibility study in diabetic foot ulcers[J]. Int Wound J, 2020, 17(5): 1366-1375.
[23]	Mundinger GS, Armstrong DG, Smith DJ, et al. Autologous Homologous Skin Constructs Allow Safe Closure of Wounds: A Retrospective, Noncontrolled, Multicentered Case Series[J]. Plast Reconstr Surg Glob Open, 2020, 8(5): e2840.
[24]	Menchini G, Astarita C. Effects of autologous micrografts on stable bilateral vitiligo: A focus on hand lesions[J]. J Dermatol, 2020, 47(12): 1417-1423.
[25]	Gupta DK, Devendra S. Microskin Grafting for Stable Vitiligo of the Penis and Vulva: Near Total Uniform Pigmentation[J]. J Cutan Med Surg, 2015, 19(5): 477-483.
[26]	Ruiz RG, Rosell JMC, Ceccarelli G, et al. Progenitor-cell-enriched micrografts as a novel option for the management of androgenetic alopecia[J]. J Cell Physiol, 2020, 235(5): 4587-4593.

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