Research progress of vascular endothelial growth factor mediated neovascularization promoting wound healing

doi:10.3877/cma.j.issn.1673-9450.2021.06.015

Abstract

Abstract:

Neovascularization is an important part of wound repair and regeneration. Vascular endothelial growth factor (VEGF), as the strongest pro-angiogenic factor, regulates many aspects of neovascularization and plays an important role in the study of neovascularization promoting wound healing. Various signaling pathways and cell components, endogenous and exogenous cytokines, traditional Chinese medicine and functional dressings all promote the expression of VEGF, and then increase new angiogenesis to promote wound healing. In this paper, the regulatory mechanism and research status of VEGF-mediated neovascularization in wound healing are reviewed to provide new ideas for promoting wound healing.

Key words: Neovascularization, physiologic, Vascular endothelial growth factors, Wound healing

Xufeng Shi, Dong Wei, Xiaoping Yu, Junli Zhou. Research progress of vascular endothelial growth factor mediated neovascularization promoting wound healing[J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2021, 16(06): 536-538.

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