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Chinese Journal of Injury Repair and Wound Healing(Electronic Edition) ›› 2022, Vol. 17 ›› Issue (02): 141-144. doi: 10.3877/cma.j.issn.1673-9450.2022.02.009

• Original Article • Previous Articles     Next Articles

Effect of stamp skin grafting combined with irrigation therapy in burn patients

Gang Zheng1, Zhi Xie2, Tao Huang1, Caizhi Gu2,()   

  1. 1. Department of Burns, Eight Affiliated Hospital of Xinjiang Medical University, Urumqi 830000, China
    2. Department of Pharmacy, General Hospital of Xinjiang Military Region, Urumqi 830000, China
  • Received:2022-01-17 Online:2022-04-01 Published:2022-05-24
  • Contact: Caizhi Gu

Abstract:

Objective

To analyze the effect of stamp skin transplantation combined with irrigation therapy in the treatment of deep burn patients.

Methods

A total of 68 patients with large-area burns were enrolled in Eight Affiliated Hospital of Xinjiang Medical University from January 2015 to January 2019. They were divided into two groups: the control group and the observation group, with each group had 34 cases, according to the random number table. The control group was treated with debridement and escharectomy(stage I), and stamp skin grafting, the observation group was combined with irrigation therapy every day until the eve of stamp skin grafting and then stamp skin grafting on this basis. The operation time, wound healing rate(stage I), recovery rate, positive rate of bacterial culture of wound secretion, survival rate of skin graft and wound healing time at 3, 7 and 15 days after operation were observed, visual analogue scale (VAS) scores were assessed before treatment, 3 months after treatment and 6 months after treatment. Data was processed with t test.

Results

The operation time of the observation group[(70.31±7.69) min] was slightly longer than that of the control group[(66.52±8.41) min], there was no statistically significant difference(t=1.939, P>0.05); The wound healing rate and recovery rate in the observation group[(77.34±7.05)%, (74.27±5.84)%] were significantly higher than those[(65.61±6.92)%, (63.41±3.35)% ] in the control group, and the positive rate of bacterial culture in wound secretion[(21.19±4.42)%] was significantly lower than that in the control group[(64.36±11.25)%], the differences were statistically significant(t= 6.924, 9.406, 20.826; P<0.05). At 3, 7, 15 days after operation, the survival rates of skin graft in the observation group [(34.11±5.26)%, (59.31±4.72)%, (3.19±1.42)%]were higher those in the control group[(28.64±11.45)%, (51.74±5.68)%, (64.71±8.25)%], the differences were statistically significant(t=2.531, 5.977, 3.717; P<0.05), moreover the wound healing time of the observation group[(3.19±1.42) d] was shorter than that of the control group[(5.36±2.25) d], the difference was statistically significant(t=4.756, P<0.05). There was no significant difference in the VAS score between the two groups before treatment(P>0.05). At 3 months and 6 months after treatment, the VAS scores of the observation group[(5.41±0.34) points, (3.35±1.09) points] were lower than those of the control group[(6.15±1.28) points, (4.37±1.24) points], and the differences were statistically significant (t=3.258, 3.603; P<0.05).

Conclusion

The application of stamp skin grafting combined with wound irrigation therapy in patients with large-area burns can effectively improve surgical indicators, improve the survival rate of skin grafting, and help to relieve pain.

Key words: Burns, Stamp skin graft, Irrigation therapy, Wound healing, Debridement

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