Abstract:
Objective To investigate the clinical therapeutic effect of modified chitin bioremediation film in treating superficial partial-thickness burn.
Methods Seventy cases of superficial partial-thickness burn came from the Department of Burns and Plastic Surgery, First Hospital of Shijiazhuang from May 2016 to May 2018 were randomly divided into the treatment group and the control group according to the random number table method, 35 cases in each group. The wounds of patients in the treatment group were disinfected by iodophor, and then washed with 0.9% sodium chloride solution to remove necrotic skin and foreign bodies, then covered with modified chitin bioremediation film externally, changed dressing once a day until wound healing; the control group also cleaned the wound surface, covered the wound surface with sterile gauze externally, and changed the dressing once a day. The wound healing rate at 7, 10, and 13 days after injury and wound average healing time, the numerical rating scale (NRS) of patients dressing pain, wound infection, scar and other adverse reactions were observed. Data were compared by t test.
Result The wound healing rate of the treatment group at 7, 10, and 13 days after injury were (83.66±3.59)%, (93.69±3.24)%, and (99.46±0.78)%, which were higher than those of the control group (81.40±3.50)%, (90.63±4.25)%, (98.57±1.63)%, the differences were statistically significant (t=2.66, 3.38, 2.90; P=0.010, 0.001, 0.006); the average healing time of the wound in the treatment group was (12.11±1.89) d, short than the control group (13.51±1.15) d, the difference was statistically significant (t=3.75, P<0.05). The NRS scale in the treatment group was (3.29±0.52) scores, which was lower than that in the control group (3.86±0.49) scores, and the difference was statistically significant (t=4.72, P<0.05). There were no infected patients in the two groups, no scar growth was observed during the follow-up of 3 months, and no other adverse reactions were found.
Conlusion The use of modified chitin bioremediation film can increase the wound healing rate and shorten the healing time of the superficial partial-thickness burn patients, and reduce the pain of patients.
Key words:
Burns,
Wound healing,
Biofilms,
Chitin
Ruipeng Sun, Jing Sun, Liankui Zhao, Dongjun Li, Qiao Huai, Lijuan Xu. Clinical therapeutic effect of modified chitin bioremediation film in treating superficial partial-thickness burn[J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2019, 14(04): 280-284.