| ［1］ |
Chung BY， Kim HB， Jung MJ，et al. Post-burn pruritus［J］. Int J Mol Sci， 2020， 21（11）：3880. DOI： 10.3390/ijms21113880.
|
| ［2］ |
McGovern C， Quasim T， Puxty K，et al. Neuropathic agents in the management of pruritus in burn injuries：a systematic review and meta-analysis［J］. Trauma Surg Acute Care Open， 2021， 6（1）：e000810. DOI： 10.1136/tsaco-2021-000810.
|
| ［3］ |
|
| ［4］ |
Aktas H， Tuncbilek Z， Hidiroğlu S. Evaluation of the effect of post-burn pruritus on patients' quality of life and experiences［J］. Burns， 2025， 52（1）：107808. DOI： 10.1016/j.burns.2025.107808.
|
| ［5］ |
Andrade LF， Abdi P， Kooner A，et al. Treatment of post-burn pruritus-a systematic review and meta-analysis［J］. Burns， 2024， 50（2）：293-301. DOI： 10.1016/j.burns.2023.09.012.
|
| ［6］ |
ISBI Practice Guidelines Committee，Steering Subcommittee，Advisory Subcommittee. ISBI practice guidelines for burn care［J］ . Burns， 2016， 42（5）：953-1021. DOI： 10.1016/j.burns.2016.05.013. |
| ［7］ |
|
| ［8］ |
Yang AF， Nguyen M， Li AW，et al. Use of technology for the objective evaluation of scratching behavior：a systematic review［J］. JAAD international， 2021， 5（1）：19-32. DOI： 10.1016/j.jdin.2021.06.005.
|
| ［9］ |
Gomułka K， Mędrala W. Serum levels of vascular endothelial growth factor，platelet activating factor and eosinophil-derived neurotoxin in chronic spontaneous urticaria-a pilot study in adult patients［J］. Int J Mol Sci， 2022， 23（17）：9631. DOI： 10.3390/ijms23179631.
|
| ［10］ |
Bolier R， de Vries ES， Parés A，et al. Fibrates for the treatment of cholestatic itch （FITCH）：study protocol for a randomized controlled trial［J］. Trials， 2017， 18（1）：230. DOI： 10.1186/s13063-017-1966-8.
|
| ［11］ |
Sakae Kaneko， Kunie Kohno， Sakae Honda，et al. Antipruritic effect of Neurotropin injection on moisturizer- and antihistamine-resistant itch in patients with pruritus：a multicenter，open-label，small sample study［J］. J Cutan Immunol Allergy， 2018， 1（3）：109-116. DOI： 10.1002/cia2.12021.
|
| ［12］ |
Ferm I， Sterner M， Wallengren J．Somatic and psychiatric comorbidity in patients with chronic pruritus［J］. Acta Derm Venereol， 2010， 90（4） ：395-400. DOI： 10.2340/00015555-0864.
|
| ［13］ |
Jiang M， Zhang Y， Xiang Q，et al. Elastic silicone occlusive sheeting versus silicone occlusive sheeting in the treatment of scars：a randomized controlled trial［J］. Dermatol Ther （Heidelb）， 2022， 12（8）：1809-1821. DOI： 10.1007/s13555-022-00763-5.
|
| ［14］ |
Hsu JK， Thibodeau R， Wong SJ，et al. A "Wii" bit of fun：the effects of adding Nintendo Wii（ ®） Bowling to a standard exercise regimen for residents of long-term care with upper extremity dysfunction［J］. Physiother Theory Pract， 2010， 27（3）：185-93. DOI： 10.3109/09593985.2010.483267.
|
| ［15］ |
Ware LJ， Epps CD， Herr K，et al. Evaluation of the revised faces pain scale，Verbal Descriptor Scale，Numeric Rating Scale，and Iowa Pain Thermometer in older minority adults［J］. Pain Manag Nurs， 2006， 7（3）：117-125. DOI： 10.1016/j.pmn.2006.06.005.
|
| ［16］ |
Phan NQ， Blome C， Fritz F，et al. Assessment of pruritus intensity：prospective study on validity and reliability of the visual analogue scale，numerical rating scale and verbal rating scale in 471 patients with chronic pruritus［J］. Acta Derm Venereol， 2012， 92（5）：502-507. DOI： 10.2340/00015555-1246.
|
| ［17］ |
Lio PA， Simpson EL， Han G，et al. Improvement in sleep and itch and enhanced quality of life in adult patients with moderate-to-severe atopic dermatitis：results from a phase 3 trial of baricitinib therapy［J］. J Dermatolog Treat， 2021， 33（4）：2057-2062. DOI： 10.1080/09546634.2021.1914308.
|
| ［18］ |
Erickson S， Kim BS. Research techniques made simple：itch measurement in clinical trials［J］. J Invest Dermatol， 2019， 139（2）：264-269. DOI： 10.1016/j.jid.2018.12.004.
|
| ［19］ |
Lee YI， Lee SG， Kim J，et al. Proteoglycan combined with hyaluronic acid and hydrolyzed collagen restores the skin barrier in mild atopic dermatitis and dry，eczema-prone skin：a pilot study［J］. Int J Mol Sci， 2021， 22（19）：10189. DOI： 10.3390/ijms221910189.
|
| ［20］ |
Helou N， Nobre D， Corre T，et al. Prevalence，severity，and determinants of CKD-associated pruritus in a Swiss hemodialysis population with widespread use of hemodiafiltration：a cross-sectional study［J］. BMC Nephrol， 2025， 26（1）：640. DOI： 10.1186/s12882-025-04570-w.
|
| ［21］ |
|
| ［22］ |
Amtmann D， McMullen K， Kim J，et al. Psychometric properties of the modified 5-D itch scale in a burn model system sample of people with burn injury［J］. J Burn Care Res， 2017， 38（1）：e402-e408. DOI： 10.1097/BCR.0000000000000404.
|
| ［23］ |
Reich A， Bożek A， Janiszewska K，et al. 12-Item pruritus severity scale：development and validation of new itch severity questionnaire［J］. Biomed Res Int， 2017：3896423. DOI： 10.1155/2017/3896423.
|
| ［24］ |
|
| ［25］ |
Aktas H， Tuncbilek Z. Validity and reliability study of 12 item pruritus severity scale for Turkish patients with burns［J］. Burns， 2025， 51（5）：107475. DOI： 10.1016/j.burns.2025.107475.
|
| ［26］ |
|
| ［27］ |
Reich A，Mędrek K，Szepietowski J. Four-item itch questionnaire–validation of questionnaire［J］. Przegl Dermatol，2012，99（5）：600-604.
|
| ［28］ |
|
| ［29］ |
|
| ［30］ |
Van Loey NE， Hofland HW， Hendrickx H，et al. Validation of the burns itch questionnaire［J］. Burns， 2016， 42（3）：526-534. DOI： 10.1016/j.burns.2015.08.001.
|
| ［31］ |
|
| ［32］ |
Nakad L， Biswas A， Leoutsakos JM，et al. Pain，itch，and psychological distress symptom clusters in burn survivors：a factor analysis［J］. Burns， 2026， 52（1）：107787. DOI： 10.1016/j.burns.2025.107787.
|
| ［33］ |
Morris V， Murphy LM， Rosenberg M，et al. Itch assessment scale for the pediatric burn survivor［J］. J Burn Care Res， 2012， 33（3）：419-424. DOI： 10.1097/BCR.0b013e3182372bfa.
|
| ［34］ |
Blankers K， Dankerlui N， van Loey N，et al. Cross-cultural validation of the itch man scale in pediatric burn survivors in a South African setting［J］. Burns， 2019， 45（3）：725-731. DOI： 10.1016/j.burns.2018.09.027.
|
| ［35］ |
Tuncbilek Z， Demir S， Karahan S，et al. Reliability and validity of the Turkish language itch man scale in pediatric burn survivors［J］ . Burns， 2025， 51（6）：107530. DOI： 10.1016/j.burns.2025.107530.
|
| ［36］ |
Everett T， Parker K， Fish J，et al. The construction and implementation of a novel postburn pruritus scale for infants and children aged five years or less：introducing the Toronto pediatric itch scale［J］. J Burn Care Res， 2015， 36（1）：44-49. DOI： 10.1097/BCR.0000000000000129.
|
| ［37］ |
Avey S， Morris M， Sargsyan D，et al. At-home evaluation of both wearable and touchless digital health technologies for measuring nocturnal scratching in atopic dermatitis：analytical validation study［J］. J Med Internet Res， 2025， 27：e72216. DOI： 10.2196/72216.
|
| ［38］ |
Price A， Cohen DE. Assessment of pruritus in patients with psoriasis and atopic dermatitis：subjective and objective tools［J］. Dermatitis， 2014， 25（6）：334-344. DOI： 10.1097/DER.0000000000000077.
|
| ［39］ |
Benjamin K， Waterston K， Russell M，et al. The development of an objective method for measuring scratch in children with atopic dermatitis suitable for clinical use［J］. J Am Acad Dermatol， 2004， 50（1）：33-40. DOI： 10.1016/s0190-9622（03）02480-0.
|
| ［40］ |
Chun KS， Kang YJ， Lee JY，et al. A skin-conformable wireless sensor to objectively quantify symptoms of pruritus［J］. Sci Adv， 2021， 7（18）：eabf9405. DOI： 10.1126/sciadv.abf9405.
|
| ［41］ |
|
| ［42］ |
Che DN， Cho BO， Shin JY，et al. Fisetin inhibits IL-31 production in stimulated human mast cells：possibilities of fisetin being exploited to treat histamine-independent pruritus［J］. Life Sci， 2018， 201：121-129. DOI： 10.1016/j.lfs.2018.03.056.
|
| ［43］ |
Raghuram K， Orlandi S， Church P，et al. Automated movement recognition to predict motor impairment in high-risk infants：a systematic review of diagnostic test accuracy and meta-analysis［J］. Dev Med Child Neurol， 2021， 63（6）：637-648. DOI： 10.1111/dmcn.14800.
|
| ［44］ |
Park I， Lee K， Bishayee K，et al. Machine-learning based automatic and real-time detection of mouse scratching behaviors［J］. Exp Neurobiol， 2019， 28（1）：54-61. DOI： 10.5607/en.2019.28.1.54.
|
| ［45］ |
Yu H， Xiong J， Ye AY，et al. Scratch-AID，a deep learning-based system for automatic detection of mouse scratching behavior with high accuracy［J］. Elife， 2022， 11：e84042. DOI： 10.7554/eLife.84042.
|
| ［46］ |
Spencer RH， Kilfeather SA， Lee E，et al. Systemic inflammatory markers correlate with chronic kidney disease-associated pruritus and response to treatment［J］. J Invest Dermatol， 2026， 146（1）：175-183. DOI： 10.1016/j.jid.2025.04.035.
|
| ［47］ |
Cesnakova L， Meadows K， Avey S，et al. A patient-centred conceptual model of nocturnal scratch and its impact in atopic dermatitis：a mixed-methods study supporting the development of novel digital measurements［J］. Skin Health Dis， 2023， 3（5）：e262. DOI： 10.1002/ski2.262.
|
| ［48］ |
Gernart M， Tsianakas A， Zeidler C，et al. ItchApp©：an app-based eDiary for assessment of chronic pruritus in clinical trials［J］ . Acta Derm Venereol， 2017， 97（5）：601-606. DOI： 10.2340/00015555-2602.
|
| ［49］ |
Schnitzler C， Rosen J， Szepietowski JC，et al. Validation of 'ItchApp©' in Poland and in the USA：multicentre validation study of an electronical diary for the assessment of pruritus［J］. J Eur Acad Dermatol Venereol， 2019， 33（2）：398-404. DOI： 10.1111/jdv.15300.
|
| ［50］ |
Ikoma A， Ebata T， Chantalat L，et al. Measurement of nocturnal scratching in patients with pruritus using a smartwatch：initial clinical studies with the Itch Tracker App［J］. Acta Derm Venereol， 2019， 99（3）：268-273. DOI： 10.2340/00015555-3105.
|
| ［51］ |
Sugiyama A， Murakami Y， Okamoto K，et al. Nocturnal scratching and quality of sleep in children with atopic dermatitis［J］. Acta Derm Venereol， 2023， 103：adv12345. DOI： 10.2340/actadv.v103.12345.
|