Role of fibroblasts heterogeneity in wound healing and scar formation

doi:10.3877/cma.j.issn.1673-9450.2021.04.013

Abstract

Abstract:

Fibroblasts are one of the important effector cells in the wound healing process and are involved in several important aspects. Different subpopulations of fibroblasts exhibit strong heterogeneity depending on different aspects of their anatomical localization, cell surface markers, and functional phenotypes. This paper reviews the heterogeneous characteristics of fibroblasts and their role in wound healing and scar formation, with the aim of providing a new theoretical basis for wound repair therapy.

Key words: Fibroblasts, Wound healing, Cicatrix, Heterogeneity

Jue Wang, Xiaohong Hu, Weifeng He. Role of fibroblasts heterogeneity in wound healing and scar formation[J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2021, 16(04): 353-357.

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https://zhssyxfzz.cma-cmc.com.cn/EN/Y2021/V16/I04/353

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